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The Electronic Property Differences between dA::dG and dA::dG(oxo). A Theoretical Approach
The dA::dG(oxo) pair appearing in nucleic ds-DNA can lead to a mutation in the genetic information. Depending on the dG(oxo) source, an AT→GC and GC→AC transversion might be observed. As a result, glycosylases are developed during the evolution, i.e., OGG1 and MutY. While the former effectively remo...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503971/ https://www.ncbi.nlm.nih.gov/pubmed/32842464 http://dx.doi.org/10.3390/molecules25173828 |