Two-Player Game in a Complex Landscape: 26S Proteasome, PKA, and Intracellular Calcium Concentration Modulate Mammalian Sperm Capacitation by Creating an Integrated Dialogue—A Computational Analysis

Recent experimental findings suggest the involvement of the 26S proteasome, the main protease active in eukaryotic cells, in the process that leads mammalian sperm to become fully fertile, so-called capacitation. Unfortunately, its role in male gametes signaling is still far from being completely un...

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Detalles Bibliográficos
Autores principales: Taraschi, Angela, Cimini, Costanza, Capacchietti, Giulia, Ramal-Sanchez, Marina, Valbonetti, Luca, Machado-Simoes, Juliana, Moussa, Fadl, Tagaram, Israiel, Mokh, Samia, Al Iskandarani, Mohamad, Colosimo, Alessia, Barboni, Barbara, Bernabò, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504021/
https://www.ncbi.nlm.nih.gov/pubmed/32872422
http://dx.doi.org/10.3390/ijms21176256

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