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Bioinformatics Methods in Medical Genetics and Genomics

Medical genomics relies on next-gen sequencing methods to decipher underlying molecular mechanisms of gene expression. This special issue collects materials originally presented at the “Centenary of Human Population Genetics” Conference-2019, in Moscow. Here we present some recent developments in co...

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Detalles Bibliográficos
Autores principales: Orlov, Yuriy L., Baranova, Ancha V., Tatarinova, Tatiana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504073/
https://www.ncbi.nlm.nih.gov/pubmed/32872128
http://dx.doi.org/10.3390/ijms21176224
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author Orlov, Yuriy L.
Baranova, Ancha V.
Tatarinova, Tatiana V.
author_facet Orlov, Yuriy L.
Baranova, Ancha V.
Tatarinova, Tatiana V.
author_sort Orlov, Yuriy L.
collection PubMed
description Medical genomics relies on next-gen sequencing methods to decipher underlying molecular mechanisms of gene expression. This special issue collects materials originally presented at the “Centenary of Human Population Genetics” Conference-2019, in Moscow. Here we present some recent developments in computational methods tested on actual medical genetics problems dissected through genomics, transcriptomics and proteomics data analysis, gene networks, protein–protein interactions and biomedical literature mining. We have selected materials based on systems biology approaches, database mining. These methods and algorithms were discussed at the Digital Medical Forum-2019, organized by I.M. Sechenov First Moscow State Medical University presenting bioinformatics approaches for the drug targets discovery in cancer, its computational support, and digitalization of medical research, as well as at “Systems Biology and Bioinformatics”-2019 (SBB-2019) Young Scientists School in Novosibirsk, Russia. Selected recent advancements discussed at these events in the medical genomics and genetics areas are based on novel bioinformatics tools.
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spelling pubmed-75040732020-09-24 Bioinformatics Methods in Medical Genetics and Genomics Orlov, Yuriy L. Baranova, Ancha V. Tatarinova, Tatiana V. Int J Mol Sci Editorial Medical genomics relies on next-gen sequencing methods to decipher underlying molecular mechanisms of gene expression. This special issue collects materials originally presented at the “Centenary of Human Population Genetics” Conference-2019, in Moscow. Here we present some recent developments in computational methods tested on actual medical genetics problems dissected through genomics, transcriptomics and proteomics data analysis, gene networks, protein–protein interactions and biomedical literature mining. We have selected materials based on systems biology approaches, database mining. These methods and algorithms were discussed at the Digital Medical Forum-2019, organized by I.M. Sechenov First Moscow State Medical University presenting bioinformatics approaches for the drug targets discovery in cancer, its computational support, and digitalization of medical research, as well as at “Systems Biology and Bioinformatics”-2019 (SBB-2019) Young Scientists School in Novosibirsk, Russia. Selected recent advancements discussed at these events in the medical genomics and genetics areas are based on novel bioinformatics tools. MDPI 2020-08-28 /pmc/articles/PMC7504073/ /pubmed/32872128 http://dx.doi.org/10.3390/ijms21176224 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Editorial
Orlov, Yuriy L.
Baranova, Ancha V.
Tatarinova, Tatiana V.
Bioinformatics Methods in Medical Genetics and Genomics
title Bioinformatics Methods in Medical Genetics and Genomics
title_full Bioinformatics Methods in Medical Genetics and Genomics
title_fullStr Bioinformatics Methods in Medical Genetics and Genomics
title_full_unstemmed Bioinformatics Methods in Medical Genetics and Genomics
title_short Bioinformatics Methods in Medical Genetics and Genomics
title_sort bioinformatics methods in medical genetics and genomics
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504073/
https://www.ncbi.nlm.nih.gov/pubmed/32872128
http://dx.doi.org/10.3390/ijms21176224
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