Cargando…

Challenges in Promoting Mitochondrial Transplantation Therapy

Mitochondrial transplantation therapy is an innovative strategy for the treatment of mitochondrial dysfunction. The approach has been reported to be useful in the treatment of cardiac ischemic reperfusion injuries in human clinical trials and has also been shown to be useful in animal studies as a m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamada, Yuma, Ito, Momo, Arai, Manae, Hibino, Mitsue, Tsujioka, Takao, Harashima, Hideyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504154/ https://www.ncbi.nlm.nih.gov/pubmed/32887310 http://dx.doi.org/10.3390/ijms21176365

Ejemplares similares

Therapeutic Strategies for Regulating Mitochondrial Oxidative Stress
por: Yamada, Yuma, et al.
Publicado: (2020)

Resveratrol-Encapsulated Mitochondria-Targeting Liposome Enhances Mitochondrial Respiratory Capacity in Myocardial Cells
por: Tsujioka, Takao, et al.
Publicado: (2021)

A system that delivers an antioxidant to mitochondria for the treatment of drug-induced liver injury
por: Hibino, Mitsue, et al.
Publicado: (2023)

Development of a Mitochondrial Targeting Lipid Nanoparticle Encapsulating Berberine
por: Hori, Ikuma, et al.
Publicado: (2023)

Condensation of Plasmid DNA Enhances Mitochondrial Association in Skeletal Muscle Following Hydrodynamic Limb Vein Injection
por: Yasuzaki, Yukari, et al.
Publicado: (2014)

Validation of a mitochondrial RNA therapeutic strategy using fibroblasts from a Leigh syndrome patient with a mutation in the mitochondrial ND3 gene
por: Yamada, Yuma, et al.
Publicado: (2020)

Transplantation of MITO cells, mitochondria activated cardiac progenitor cells, to the ischemic myocardium of mouse enhances the therapeutic effect
por: Sasaki, Daisuke, et al.
Publicado: (2022)

Investigation of siRNA Nanoparticle Formation Using Mono-Cationic Detergents and Its Use in Gene Silencing in Human HeLa Cells
por: Yamada, Yuma, et al.
Publicado: (2013)

Evolution of drug delivery system from viewpoint of controlled intracellular trafficking and selective tissue targeting toward future nanomedicine
por: Yamada, Yuma, et al.
Publicado: (2020)

Validation of Gene Therapy for Mutant Mitochondria by Delivering Mitochondrial RNA Using a MITO-Porter
por: Kawamura, Eriko, et al.
Publicado: (2020)

Current Status and Challenges Associated with CNS-Targeted Gene Delivery across the BBB
por: Kimura, Seigo, et al.
Publicado: (2020)

The manner in which DNA is packaged with TFAM has an impact on transcription activation and inhibition
por: Furukawa, Ryo, et al.
Publicado: (2012)

An effective in vivo mitochondria-targeting nanocarrier combined with a π-extended porphyrin-type photosensitizer
por: Satrialdi,, et al.
Publicado: (2021)

Differences in the Intracellular Localization of Methylated β-Cyclodextrins-Threaded Polyrotaxanes Lead to Different Cellular States
por: Yamada, Yuma, et al.
Publicado: (2023)

Retrograde Axonal Transport of Liposomes from Peripheral Tissue to Spinal Cord and DRGs by Optimized Phospholipid and CTB Modification
por: Fukui, Takafumi, et al.
Publicado: (2022)

Targeting Tumor Endothelial Cells with Nanoparticles
por: Sakurai, Yu, et al.
Publicado: (2019)

Non-invasive gene delivery across the blood-brain barrier: present and future perspectives
por: Kimura, Seigo, et al.
Publicado: (2021)

Strategies for fighting pandemic virus infections: Integration of virology and drug delivery
por: Nakamura, Takashi, et al.
Publicado: (2022)

Mitochondrial Transplantation in Mitochondrial Medicine: Current Challenges and Future Perspectives
por: D’Amato, Marco, et al.
Publicado: (2023)

Cytoprotective role of the fatty acid binding protein 4 against oxidative and endoplasmic reticulum stress in 3T3-L1 adipocytes
por: Kajimoto, Kazuaki, et al.
Publicado: (2014)

Optimization of a siRNA Carrier Modified with a pH-Sensitive Cationic Lipid and a Cyclic RGD Peptide for Efficiently Targeting Tumor Endothelial Cells
por: Hada, Tomoya, et al.
Publicado: (2015)

Elimination of the biphasic pharmacodynamics of 15d-PGJ2 by controlling its release from a nanoemulsion
por: Abbasi, Saed, et al.
Publicado: (2016)

Mixing lipids to manipulate the ionization status of lipid nanoparticles for specific tissue targeting
por: Shobaki, Nour, et al.
Publicado: (2018)

Effective Therapy Using a Liposomal siRNA that Targets the Tumor Vasculature in a Model Murine Breast Cancer with Lung Metastasis
por: Sakurai, Yu, et al.
Publicado: (2018)

Current progress of mitochondrial transplantation that promotes neuronal regeneration
por: Chang, Chu-Yuan, et al.
Publicado: (2019)

mRNA-Loaded Lipid Nanoparticles Targeting Immune Cells in the Spleen for Use as Cancer Vaccines
por: Shimosakai, Ryoya, et al.
Publicado: (2022)

In vitro optimization of 2′-OMe-4′-thioribonucleoside–modified anti-microRNA oligonucleotides and its targeting delivery to mouse liver using a liposomal nanoparticle
por: Takahashi, Mayumi, et al.
Publicado: (2013)

Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex
por: Hama, Susumu, et al.
Publicado: (2007)

Effect of the Compaction and the Size of DNA on the Nuclear Transfer Efficiency after Microinjection in Synchronized Cells
por: Akita, Hidetaka, et al.
Publicado: (2015)

The silencing of indoleamine 2,3-dioxygenase 1 (IDO1) in dendritic cells by siRNA-loaded lipid nanoparticles enhances cell-based cancer immunotherapy
por: Endo, Rikito, et al.
Publicado: (2019)

mRNA-Loaded Lipid Nanoparticles Targeting Dendritic Cells for Cancer Immunotherapy
por: Sasaki, Kosuke, et al.
Publicado: (2022)

Development of a Novel DNA Aptamer Ligand Targeting to Primary Cultured Tumor Endothelial Cells by a Cell-Based SELEX Method
por: Ara, Mst. Naznin, et al.
Publicado: (2012)

A KALA-modified lipid nanoparticle containing CpG-free plasmid DNA as a potential DNA vaccine carrier for antigen presentation and as an immune-stimulative adjuvant
por: Miura, Naoya, et al.
Publicado: (2015)

Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
por: Arimori, Takao, et al.
Publicado: (2011)

Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers
por: Maeki, Masatoshi, et al.
Publicado: (2017)

Mitochondrial transplantation: opportunities and challenges in the treatment of obesity, diabetes, and nonalcoholic fatty liver disease
por: Chen, Yifei, et al.
Publicado: (2022)

Unique molecular mechanisms for maintenance and alteration of genetic information in the budding yeast Saccharomyces cerevisiae
por: Ito-Harashima, Sayoko, et al.
Publicado: (2017)

Reporter gene assays for screening and identification of novel molting hormone- and juvenile hormone-like chemicals
por: Ito-Harashima, Sayoko, et al.
Publicado: (2021)

Intracellular stability of 2′-OMe-4′-thioribonucleoside modified siRNA leads to long-term RNAi effect
por: Takahashi, Mayumi, et al.
Publicado: (2012)

Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines
por: Nakamura, Takashi, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4uatke3bpbjif0bbdaoul3e83d