Synergistic Interactions of 5-Fluorouracil with Inhibitors of Protein Kinase CK2 Correlate with p38 MAPK Activation and FAK Inhibition in the Triple-Negative Breast Cancer Cell Line

Background: The combination effect of 5-fluorouracil (5-FU) with either CX-4945 or a new inhibitor of protein kinase CK2, namely 14B (4,5,6,7-tetrabromo-1-(3-bromopropyl)-2-methyl-1H-benzimidazole), on the viability of MCF-7 and triple-negative MDA-MB-231 breast cancer cell lines was studied. Method...

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Detalles Bibliográficos
Autores principales: Wińska, Patrycja, Karatsai, Olena, Staniszewska, Monika, Koronkiewicz, Mirosława, Chojnacki, Konrad, Rędowicz, Maria Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504329/
https://www.ncbi.nlm.nih.gov/pubmed/32872257
http://dx.doi.org/10.3390/ijms21176234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504329/
https://www.ncbi.nlm.nih.gov/pubmed/32872257
http://dx.doi.org/10.3390/ijms21176234

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