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Merged Tacrine-Based, Multitarget-Directed Acetylcholinesterase Inhibitors 2015–Present: Synthesis and Biological Activity

Acetylcholinesterase is an important biochemical enzyme in that it controls acetylcholine-mediated neuronal transmission in the central nervous system, contains a unique structure with two binding sites connected by a gorge region, and it has historically been the main pharmacological target for tre...

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Detalles Bibliográficos
Autores principales:	Eckroat, Todd J., Manross, Danielle L., Cowan, Seth C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504404/ https://www.ncbi.nlm.nih.gov/pubmed/32825138 http://dx.doi.org/10.3390/ijms21175965

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