Cargando…
Metabolite Patterns in Human Myeloid Hematopoiesis Result from Lineage-Dependent Active Metabolic Pathways
Assessment of hematotoxicity from environmental or xenobiotic compounds is of notable interest and is frequently assessed via the colony forming unit (CFU) assay. Identification of the mode of action of single compounds is of further interest, as this often enables transfer of results across differe...
Autores principales: | Kaiser, Lars, Weinschrott, Helga, Quint, Isabel, Blaess, Markus, Csuk, René, Jung, Manfred, Kohl, Matthias, Deigner, Hans-Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504406/ https://www.ncbi.nlm.nih.gov/pubmed/32847028 http://dx.doi.org/10.3390/ijms21176092 |
Ejemplares similares
-
Drugs, Metabolites, and Lung Accumulating Small Lysosomotropic Molecules: Multiple Targeting Impedes SARS-CoV-2 Infection and Progress to COVID-19
por: Blaess, Markus, et al.
Publicado: (2021) -
Lineage-Selective Disturbance of Early Human Hematopoietic Progenitor Cell Differentiation by the Commonly Used Plasticizer Di-2-ethylhexyl Phthalate via Reactive Oxygen Species: Fatty Acid Oxidation Makes the Difference
por: Kaiser, Lars, et al.
Publicado: (2021) -
COVID-19/SARS-CoV-2 Infection: Lysosomes and Lysosomotropism Implicate New Treatment Strategies and Personal Risks
por: Blaess, Markus, et al.
Publicado: (2020) -
Drug triggered pruritus, rash, papules, and blisters – is AGEP a clash of an altered sphingolipid-metabolism and lysosomotropism of drugs accumulating in the skin?
por: Blaess, Markus, et al.
Publicado: (2021) -
Rational Drug Repurposing: Focus on Lysosomotropism, Targets in Disease Process, Drug Profile, and Pulmonary Tissue Accumulation in SARS-CoV-2 Infection/COVID-19
por: Blaess, Markus, et al.
Publicado: (2020)