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N-Terminal Regions of Prion Protein: Functions and Roles in Prion Diseases
The normal cellular isoform of prion protein, designated PrP(C), is constitutively converted to the abnormally folded, amyloidogenic isoform, PrP(Sc), in prion diseases, which include Creutzfeldt-Jakob disease in humans and scrapie and bovine spongiform encephalopathy in animals. PrP(C) is a membran...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504422/ https://www.ncbi.nlm.nih.gov/pubmed/32872280 http://dx.doi.org/10.3390/ijms21176233 |