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Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients

A new type of sheet porous structures with functionally gradients based on triply periodic minimal surfaces (TPMS) is proposed for designing bone scaffolds. The graded structures were generated by constructing branched features with different number of sheets. The design of the structure was formula...

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Detalles Bibliográficos
Autores principales: Jin, Yuan, Kong, Haoyu, Zhou, Xueyong, Li, Guangyong, Du, Jianke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504448/
https://www.ncbi.nlm.nih.gov/pubmed/32878196
http://dx.doi.org/10.3390/ma13173844
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author Jin, Yuan
Kong, Haoyu
Zhou, Xueyong
Li, Guangyong
Du, Jianke
author_facet Jin, Yuan
Kong, Haoyu
Zhou, Xueyong
Li, Guangyong
Du, Jianke
author_sort Jin, Yuan
collection PubMed
description A new type of sheet porous structures with functionally gradients based on triply periodic minimal surfaces (TPMS) is proposed for designing bone scaffolds. The graded structures were generated by constructing branched features with different number of sheets. The design of the structure was formulated mathematically and five types of porous structure with different structural features were used for investigation. The relative density (RD) and surface area to volume (SA/V) ratio of the samples were analyzed using a slice-based approach to confirm their relationships with design parameters. All samples were additively manufactured using selective laser melting (SLM), and their physical morphologies were observed and compared with the designed models. Compression tests were adopted to study the mechanical properties of the proposed structure from the obtained stress–strain curves. The results reveal that the proposed branched-sheet structures could enhance and diversify the physical and mechanical properties, indicating that it is a potential method to tune the biomechanical properties of porous scaffolds for bone tissue engineering (TE).
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spelling pubmed-75044482020-09-24 Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients Jin, Yuan Kong, Haoyu Zhou, Xueyong Li, Guangyong Du, Jianke Materials (Basel) Article A new type of sheet porous structures with functionally gradients based on triply periodic minimal surfaces (TPMS) is proposed for designing bone scaffolds. The graded structures were generated by constructing branched features with different number of sheets. The design of the structure was formulated mathematically and five types of porous structure with different structural features were used for investigation. The relative density (RD) and surface area to volume (SA/V) ratio of the samples were analyzed using a slice-based approach to confirm their relationships with design parameters. All samples were additively manufactured using selective laser melting (SLM), and their physical morphologies were observed and compared with the designed models. Compression tests were adopted to study the mechanical properties of the proposed structure from the obtained stress–strain curves. The results reveal that the proposed branched-sheet structures could enhance and diversify the physical and mechanical properties, indicating that it is a potential method to tune the biomechanical properties of porous scaffolds for bone tissue engineering (TE). MDPI 2020-08-31 /pmc/articles/PMC7504448/ /pubmed/32878196 http://dx.doi.org/10.3390/ma13173844 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jin, Yuan
Kong, Haoyu
Zhou, Xueyong
Li, Guangyong
Du, Jianke
Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients
title Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients
title_full Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients
title_fullStr Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients
title_full_unstemmed Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients
title_short Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients
title_sort design and characterization of sheet-based gyroid porous structures with bioinspired functional gradients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504448/
https://www.ncbi.nlm.nih.gov/pubmed/32878196
http://dx.doi.org/10.3390/ma13173844
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