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Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients
A new type of sheet porous structures with functionally gradients based on triply periodic minimal surfaces (TPMS) is proposed for designing bone scaffolds. The graded structures were generated by constructing branched features with different number of sheets. The design of the structure was formula...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504448/ https://www.ncbi.nlm.nih.gov/pubmed/32878196 http://dx.doi.org/10.3390/ma13173844 |
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author | Jin, Yuan Kong, Haoyu Zhou, Xueyong Li, Guangyong Du, Jianke |
author_facet | Jin, Yuan Kong, Haoyu Zhou, Xueyong Li, Guangyong Du, Jianke |
author_sort | Jin, Yuan |
collection | PubMed |
description | A new type of sheet porous structures with functionally gradients based on triply periodic minimal surfaces (TPMS) is proposed for designing bone scaffolds. The graded structures were generated by constructing branched features with different number of sheets. The design of the structure was formulated mathematically and five types of porous structure with different structural features were used for investigation. The relative density (RD) and surface area to volume (SA/V) ratio of the samples were analyzed using a slice-based approach to confirm their relationships with design parameters. All samples were additively manufactured using selective laser melting (SLM), and their physical morphologies were observed and compared with the designed models. Compression tests were adopted to study the mechanical properties of the proposed structure from the obtained stress–strain curves. The results reveal that the proposed branched-sheet structures could enhance and diversify the physical and mechanical properties, indicating that it is a potential method to tune the biomechanical properties of porous scaffolds for bone tissue engineering (TE). |
format | Online Article Text |
id | pubmed-7504448 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75044482020-09-24 Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients Jin, Yuan Kong, Haoyu Zhou, Xueyong Li, Guangyong Du, Jianke Materials (Basel) Article A new type of sheet porous structures with functionally gradients based on triply periodic minimal surfaces (TPMS) is proposed for designing bone scaffolds. The graded structures were generated by constructing branched features with different number of sheets. The design of the structure was formulated mathematically and five types of porous structure with different structural features were used for investigation. The relative density (RD) and surface area to volume (SA/V) ratio of the samples were analyzed using a slice-based approach to confirm their relationships with design parameters. All samples were additively manufactured using selective laser melting (SLM), and their physical morphologies were observed and compared with the designed models. Compression tests were adopted to study the mechanical properties of the proposed structure from the obtained stress–strain curves. The results reveal that the proposed branched-sheet structures could enhance and diversify the physical and mechanical properties, indicating that it is a potential method to tune the biomechanical properties of porous scaffolds for bone tissue engineering (TE). MDPI 2020-08-31 /pmc/articles/PMC7504448/ /pubmed/32878196 http://dx.doi.org/10.3390/ma13173844 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Jin, Yuan Kong, Haoyu Zhou, Xueyong Li, Guangyong Du, Jianke Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients |
title | Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients |
title_full | Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients |
title_fullStr | Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients |
title_full_unstemmed | Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients |
title_short | Design and Characterization of Sheet-Based Gyroid Porous Structures with Bioinspired Functional Gradients |
title_sort | design and characterization of sheet-based gyroid porous structures with bioinspired functional gradients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504448/ https://www.ncbi.nlm.nih.gov/pubmed/32878196 http://dx.doi.org/10.3390/ma13173844 |
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