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Transient Receptor Potential Melastatin 2 (TRPM2) Inhibition by Antioxidant, N-Acetyl-l-Cysteine, Reduces Global Cerebral Ischemia-Induced Neuronal Death

A variety of pathogenic mechanisms, such as cytoplasmic calcium/zinc influx, reactive oxygen species production, and ionic imbalance, have been suggested to play a role in cerebral ischemia induced neurodegeneration. During the ischemic state that occurs after stroke or heart attack, it is observed...

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Detalles Bibliográficos
Autores principales: Hong, Dae Ki, Kho, A Ra, Lee, Song Hee, Jeong, Jeong Hyun, Kang, Beom Seok, Kang, Dong Hyeon, Park, Min Kyu, Park, Kyoung-Ha, Lim, Man-Sup, Choi, Bo Young, Suh, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504640/
https://www.ncbi.nlm.nih.gov/pubmed/32825703
http://dx.doi.org/10.3390/ijms21176026