Genetic and Epigenetic Mechanisms Underlying Vascular Smooth Muscle Cell Phenotypic Modulation in Abdominal Aortic Aneurysm

Abdominal aortic aneurysm (AAA) refers to the localized dilatation of the infra-renal aorta, in which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of the extracellular matrix (ECM), vascular inflammation, and oxidative stress are hallmarks of AAA pathogenesis and co...

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Detalles Bibliográficos
Autores principales: Gurung, Rijan, Choong, Andrew Mark, Woo, Chin Cheng, Foo, Roger, Sorokin, Vitaly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504666/
https://www.ncbi.nlm.nih.gov/pubmed/32878347
http://dx.doi.org/10.3390/ijms21176334

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