Direct Binding of Cisplatin to p22phox, an Endoplasmic Reticulum (ER) Membrane Protein, Contributes to Cisplatin Resistance in Oral Squamous Cell Carcinoma (OSCC) Cells

Prolonged treatment with cisplatin (CDDP) frequently develops chemoresistance. We have previously shown that p22phox, an endoplasmic reticulum (ER) membrane protein, confers CDDP resistance by blocking CDDP nuclear entry in oral squamous cell carcinoma (OSCC) cells; however, the underlying mechanism...

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Detalles Bibliográficos
Autores principales: Hung, Chih-Chang, Li, Fu-An, Liang, Shih-Shin, Wang, Ling-Feng, Lin, I-Ling, Chiu, Chien-Chih, Lee, Chiu-Hsien, Chen, Jeff Yi-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504690/
https://www.ncbi.nlm.nih.gov/pubmed/32825798
http://dx.doi.org/10.3390/molecules25173815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504690/
https://www.ncbi.nlm.nih.gov/pubmed/32825798
http://dx.doi.org/10.3390/molecules25173815

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