Cargando…

A Lanosteryl Triterpene (RA-3) Exhibits Antihyperuricemic and Nephroprotective Effects in Rats

Considering the global health threat posed by kidney disease burden, a search for new nephroprotective drugs from our local flora could prove a powerful strategy to respond to this health threat. In this study we investigated the antihyperuricemic and nephroprotective potential of RA-3, a plant-deri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hlophe, Nomadlozi Blessings, Opoku, Andrew Rowland, Osunsanmi, Foluso Oluwagbemiga, Djarova-Daniels, Trayana Georgieva, Lawal, Oladipupo Adejumobi, Mosa, Rebamang Anthony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504802/ https://www.ncbi.nlm.nih.gov/pubmed/32887389 http://dx.doi.org/10.3390/molecules25174010

Ejemplares similares

A Lanosteryl Triterpene from Protorhus longifolia Improves Glucose Tolerance and Pancreatic Beta Cell Ultrastructure in Type 2 Diabetic Rats
por: Mabhida, Sihle E., et al.
Publicado: (2017)

In vivo anti-hyperlipidemic activity of the triterpene from the stem bark of Protorhus longifolia (Benrh) Engl
por: Machaba, Kgothatso E, et al.
Publicado: (2014)

In Vivo Antihyperglycemic Activity of a Lanosteryl Triterpene from Protorhus longifolia
por: Mosa, Rebamang A., et al.
Publicado: (2015)

A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats
por: Ephraim, Mabhida Sihle, et al.
Publicado: (2018)

Correction to: A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats
por: Mabhida, Sihle Ephraim, et al.
Publicado: (2018)

Evaluation of the anti-Listeria potentials of some plant-derived triterpenes
por: Penduka, Dambudzo, et al.
Publicado: (2014)

Proteomic Analysis of Differentially-Expressed Proteins in the Liver of Streptozotocin-Induced Diabetic Rats Treated with Parkia biglobosa Protein Isolate
por: Ogunyinka, Bolajoko Idiat, et al.
Publicado: (2018)

Protective Effects of Parkia biglobosa Protein Isolate on Streptozotocin-Induced Hepatic Damage and Oxidative Stress in Diabetic Male Rats
por: Ogunyinka, Bolajoko Idiat, et al.
Publicado: (2017)

Protein Isolate from Parkia biglobosa Seeds Improves Dyslipidaemia and Cardiac Oxidative Stress in Streptozotocin-Induced Diabetic Rats
por: Ogunyinka, Bolajoko Idiat, et al.
Publicado: (2019)

Isolation and Characterization of Potential Lignin Peroxidase-Producing Bacteria from Compost Samples at Richards Bay (South Africa)
por: Dube, Sindiswa L., et al.
Publicado: (2023)

Molecular basis of the anti-hyperglycemic activity of RA-3 in hyperlipidemic and streptozotocin-induced type 2 diabetes in rats
por: Mabhida, Sihle Ephraim, et al.
Publicado: (2019)

Modulatory Effect of Methanol Extract of Piper guineense in CCl(4)-Induced Hepatotoxicity in Male Rats
por: Oyinloye, Babatunji Emmanuel, et al.
Publicado: (2017)

Antihyperuricemic Effect of Urolithin A in Cultured Hepatocytes and Model Mice
por: Adachi, Shin-ichi, et al.
Publicado: (2020)

Antihyperuricemic Effect of Dendropanax morbifera Leaf Extract in Rodent Models
por: Lee, Dongho, et al.
Publicado: (2021)

Toxicity Profiling and Antihyperuricemic Activity of Goubion: A Polyherbal Formulation
por: Sadia, Halima, et al.
Publicado: (2023)

Toxicological Evaluation of Saposhnikoviae Radix Water Extract and its Antihyperuricemic Potential
por: Kim, Chang Won, et al.
Publicado: (2019)

Aqueous extract of Monodora myristica ameliorates cadmium-induced hepatotoxicity in male rats
por: Oyinloye, Babatunji Emmanuel, et al.
Publicado: (2016)

Comparative study on proximate, functional, mineral, and antinutrient composition of fermented, defatted, and protein isolate of Parkia biglobosa seed
por: Ogunyinka, Bolajoko I., et al.
Publicado: (2016)

Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics
por: Terkeltaub, Robert, et al.
Publicado: (2006)

Evaluation of the Antihyperuricemic Activity of Phytochemicals from Davallia formosana by Enzyme Assay and Hyperuricemic Mice Model
por: Chen, Chen-Yu, et al.
Publicado: (2014)

Testicular Dysfunction Ameliorative Effect of the Methanolic Roots Extracts of Maytenus procumbens and Ozoroa paniculosa
por: Cele, Nkosinathi David, et al.
Publicado: (2017)

Pharmacological Basis for Use of Selaginella moellendorffii in Gouty Arthritis: Antihyperuricemic, Anti-Inflammatory, and Xanthine Oxidase Inhibition
por: Zhao, Ping, et al.
Publicado: (2017)

Chemical investigation of Hyptis suaveolens seed, a potential antihyperuricemic nutraceutical, with assistance of HPLC-SPE-NMR
por: Hsu, Fu-Chun, et al.
Publicado: (2019)

Establishing a proof of concept for the effects of low-carbohydrate, high-fat diet (LCHFD) and physical activity on body composition in type 2 diabetes
por: Breukelman, Gerrit J., et al.
Publicado: (2021)

Corrigendum to “Pharmacological Basis for Use of Selaginella moellendorffii in Gouty Arthritis: Antihyperuricemic, Anti-Inflammatory, and Xanthine Oxidase Inhibition”
por: Zhao, Ping, et al.
Publicado: (2018)

Nephroprotective Properties of Antidiabetic Drugs
por: Gerdes, Christian, et al.
Publicado: (2023)

Impact of Polyethylene Glycol Functionalization of Graphene Oxide on Anticoagulation and Haemolytic Properties of Human Blood
por: Kamenska, Trayana, et al.
Publicado: (2021)

Antihyperuricemic effect of mangiferin aglycon derivative J99745 by inhibiting xanthine oxidase activity and urate transporter 1 expression in mice
por: Qin, Zhizhen, et al.
Publicado: (2018)

Mechanisms of Herbal Nephroprotection in diabetes mellitus
por: Dragoș, Dorin, et al.
Publicado: (2020)

New Insights into the Nephroprotective Potential of Lercanidipine
por: Hajdys, Joanna, et al.
Publicado: (2023)

Triterpenoids from Protorhus longifolia Exhibit Hypocholesterolemic Potential via Regulation of Cholesterol Biosynthesis and Stimulation of Low-Density Lipoprotein Uptake in HepG2 Cells
por: Ndlovu, Musawenkosi, et al.
Publicado: (2023)

Antihyperuricemic and xanthine oxidase inhibitory activities of Tribulus arabicus and its isolated compound, ursolic acid: In vitro and in vivo investigation and docking simulations
por: Abu-Gharbieh, Eman, et al.
Publicado: (2018)

Nephroprotective Effect of Heparanase in Experimental Nephrotic Syndrome
por: Assady, Suheir, et al.
Publicado: (2015)

Phosphodiesterase-5 inhibitors: Emerging nephroprotective drugs
por: Abassi, Zaid, et al.
Publicado: (2015)

Nephroprotection by SGLT2 Inhibition: Back to the Future?
por: De Nicola, Luca, et al.
Publicado: (2020)

Nephroprotective, cytotoxic and antioxidant activities of Euphorbia paralias
por: Al-Yousef, Hanan M., et al.
Publicado: (2021)

Effect of sodium–glucose cotransporter 2 inhibitor medication on new prescriptions of antihypertensives, antigout/antihyperuricemics and antidyslipidemics in Japan: Analysis using the JMDC Claims Database
por: Gouda, Maki, et al.
Publicado: (2022)

Triterpene einschließlich Steroide
por: Sticher, O.
Publicado: (2007)

Triterpene einschließlich Steroide
por: Sticher, Otto
Publicado: (2009)

Immunomodulatory properties of triterpenes
por: Renda, Gülin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cp1piuk0jutfuqic6gv4bgfq49