Cargando…
Formicamycin biosynthesis involves a unique reductive ring contraction
Fasamycin natural products are biosynthetic precursors of the formicamycins. Both groups of compounds are polyketide natural products that exhibit potent antibacterial activity despite displaying different three-dimensional topologies. We show here that transformation of fasamycin into formicamycin...
Autores principales: | Qin, Zhiwei, Devine, Rebecca, Booth, Thomas J., Farrar, Elliot H. E., Grayson, Matthew N., Hutchings, Matthew I., Wilkinson, Barrie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504897/ https://www.ncbi.nlm.nih.gov/pubmed/33033611 http://dx.doi.org/10.1039/d0sc01712d |
Ejemplares similares
-
Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants
por: Qin, Zhiwei, et al.
Publicado: (2017) -
Re-wiring the regulation of the formicamycin biosynthetic gene cluster to enable the development of promising antibacterial compounds
por: Devine, Rebecca, et al.
Publicado: (2021) -
Heterologous
Expression of the Formicamycin Biosynthetic
Gene Cluster Unveils Glycosylated Fasamycin Congeners
por: McDonald, Hannah P., et al.
Publicado: (2023) -
A role for antibiotic biosynthesis monooxygenase domain proteins in fidelity control during aromatic polyketide biosynthesis
por: Qin, Zhiwei, et al.
Publicado: (2019) -
Dissolution of the Disparate: Co-ordinate Regulation in Antibiotic Biosynthesis
por: McLean, Thomas C., et al.
Publicado: (2019)