Alcohol and Liver Clock Disruption Increase Small Droplet Macrosteatosis, Alter Lipid Metabolism and Clock Gene mRNA Rhythms, and Remodel the Triglyceride Lipidome in Mouse Liver

Heavy alcohol drinking dysregulates lipid metabolism, promoting hepatic steatosis – the first stage of alcohol-related liver disease (ALD). The molecular circadian clock plays a major role in synchronizing daily rhythms in behavior and metabolism and clock disruption can cause pathology, including l...

Descripción completa

Detalles Bibliográficos
Autores principales: Valcin, Jennifer A., Udoh, Uduak S., Swain, Telisha M., Andringa, Kelly K., Patel, Chirag R., Al Diffalha, Sameer, Baker, Paul R. S., Gamble, Karen L., Bailey, Shannon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504911/
https://www.ncbi.nlm.nih.gov/pubmed/33013449
http://dx.doi.org/10.3389/fphys.2020.01048

Ejemplares similares

Ejemplares similares