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Neurodegeneration of Trigeminal Mesencephalic Neurons by the Tooth Loss Triggers the Progression of Alzheimer’s Disease in 3×Tg-AD Model Mice

BACKGROUND: The mesencephalic trigeminal nucleus (Vmes) is not only anatomically adjacent to the locus coeruleus (LC) but is also tightly associated with the function of the LC. The LC can be the first area in which Alzheimer’s disease (AD) develops, although it is unclear how LC neuronal loss occur...

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Detalles Bibliográficos
Autores principales: Goto, Tetsuya, Kuramoto, Eriko, Dhar, Ashis, Wang, Rachel Pei-Hsuan, Seki, Haruka, Iwai, Haruki, Yamanaka, Atsushi, Matsumoto, Shin-Ei, Hara, Hiromitsu, Michikawa, Makoto, Ohyagi, Yasumasa, Leung, Wai Keung, Chang, Raymond Chuen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505011/
https://www.ncbi.nlm.nih.gov/pubmed/32651317
http://dx.doi.org/10.3233/JAD-200257