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Neurodegeneration of Trigeminal Mesencephalic Neurons by the Tooth Loss Triggers the Progression of Alzheimer’s Disease in 3×Tg-AD Model Mice
BACKGROUND: The mesencephalic trigeminal nucleus (Vmes) is not only anatomically adjacent to the locus coeruleus (LC) but is also tightly associated with the function of the LC. The LC can be the first area in which Alzheimer’s disease (AD) develops, although it is unclear how LC neuronal loss occur...
Autores principales: | Goto, Tetsuya, Kuramoto, Eriko, Dhar, Ashis, Wang, Rachel Pei-Hsuan, Seki, Haruka, Iwai, Haruki, Yamanaka, Atsushi, Matsumoto, Shin-Ei, Hara, Hiromitsu, Michikawa, Makoto, Ohyagi, Yasumasa, Leung, Wai Keung, Chang, Raymond Chuen-Chung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505011/ https://www.ncbi.nlm.nih.gov/pubmed/32651317 http://dx.doi.org/10.3233/JAD-200257 |
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