Cargando…

SMIT (Sodium-Myo-Inositol Transporter) 1 Regulates Arterial Contractility Through the Modulation of Vascular Kv7 Channels

OBJECTIVE: The SMIT1 (sodium:myo-inositol transporter 1) regulates myo-inositol movement into cells and responses to hypertonic stimuli. Alteration of myo-inositol levels has been associated with several diseases, including hypertension, but there is no evidence of a functional role of SMIT1 in the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barrese, Vincenzo, Stott, Jennifer B., Baldwin, Samuel N., Mondejar-Parreño, Gema, Greenwood, Iain A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Basic Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505149/ https://www.ncbi.nlm.nih.gov/pubmed/32787517 http://dx.doi.org/10.1161/ATVBAHA.120.315096

Ejemplares similares

Kv7 Channels in Lung Diseases
por: Mondejar-Parreño, Gema, et al.
Publicado: (2020)

K(V)7 Channel Expression and Function Within Rat Mesenteric Endothelial Cells
por: Baldwin, Samuel N., et al.
Publicado: (2020)

Synergistic interplay of Gβγ and phosphatidylinositol 4,5-bisphosphate dictates Kv7.4 channel activity
por: Povstyan, Oleksandr V., et al.
Publicado: (2016)

Key role for Kv11.1 (ether‐a‐go‐go related gene) channels in rat bladder contractility
por: Barrese, Vincenzo, et al.
Publicado: (2023)

Myo-inositol reduces β-catenin activation in colitis
por: Bradford, Emily M, et al.
Publicado: (2017)

The contribution of Kv7 channels to pregnant mouse and human myometrial contractility
por: McCallum, Laura A, et al.
Publicado: (2011)

Proliferative Role of Kv11 Channels in Murine Arteries
por: Barrese, Vincenzo, et al.
Publicado: (2017)

The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels
por: Greenwood, Iain A., et al.
Publicado: (2020)

Editorial: Kv7 Channels: Structure, Physiology, and Pharmacology
por: Jepps, Thomas A., et al.
Publicado: (2021)

Kv7 and Kv11 channels in myometrial regulation
por: Greenwood, Iain A, et al.
Publicado: (2014)

Effects of myo-inositol plus alpha-lactalbumin in myo-inositol-resistant PCOS women
por: Montanino Oliva, Mario, et al.
Publicado: (2018)

MARCKS mediates vascular contractility through regulating interactions between voltage-gated Ca(2+) channels and PIP(2)
por: Jahan, Kazi S., et al.
Publicado: (2020)

Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate
por: Bizzarri, Mariano, et al.
Publicado: (2016)

2-Benzyl-myo-inositol monohydrate
por: Fröhlich, Richard F. G., et al.
Publicado: (2009)

TonEBP and SMIT expression in human placenta
por: Shin, Jung-A, et al.
Publicado: (2012)

Hendrick Cornelius van dèr Wat Smit
Publicado: (1922)

Transcriptomic profile of cationic channels in human pulmonary arterial hypertension
por: Perez-Vizcaino, Francisco, et al.
Publicado: (2021)

Dynein regulates Kv7.4 channel trafficking from the cell membrane
por: van der Horst, Jennifer, et al.
Publicado: (2021)

Stereoselective Voltammetric Biosensor for Myo-Inositol and D-Chiro-Inositol Recognition
por: Tortolini, Cristina, et al.
Publicado: (2023)

Myo-inositol oxygenase is important for the removal of excess myo-inositol from syncytia induced by Heterodera schachtii in Arabidopsis roots
por: Siddique, Shahid, et al.
Publicado: (2014)

Myo-Inositol in the Treatment of Teenagers Affected by PCOS
por: Pkhaladze, Lali, et al.
Publicado: (2016)

Hysteresis in myo‐inositol utilization by Salmonella Typhimurium
por: Hellinckx, Jessica, et al.
Publicado: (2016)

Role of myo-inositol during skotomorphogenesis in Arabidopsis
por: Sharma, Naveen, et al.
Publicado: (2020)

Myo-D-inositol Trisphosphate Signalling in Oomycetes
por: Nair, Indu Muraleedharan, et al.
Publicado: (2022)

The Effectiveness of Myo-Inositol and D-Chiro Inositol Treatment in Type 2 Diabetes
por: Pintaudi, Basilio, et al.
Publicado: (2016)

Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats
por: Kandashvili, Manana, et al.
Publicado: (2022)

Comparing the Efficacy of Myo-Inositol Plus α-Lactalbumin vs. Myo-Inositol Alone on Reproductive and Metabolic Disturbances of Polycystic Ovary Syndrome
por: Kamenov, Zdravko, et al.
Publicado: (2023)

Harnessing (13)C-labeled myo-inositol to interrogate inositol phosphate messengers by NMR
por: Harmel, Robert K., et al.
Publicado: (2019)

Inhibited inositol monophosphatase and decreased myo‐inositol concentration improve wasting in skeletal muscles
por: Lee, Ji‐Hyung, et al.
Publicado: (2020)

Inositol in Disease and Development: Roles of Catabolism via myo-Inositol Oxygenase in Drosophila melanogaster
por: Contreras, Altagracia, et al.
Publicado: (2023)

Valproate regulates inositol synthesis by reducing expression of myo-inositol-3-phosphate synthase
por: Case, Kendall C., et al.
Publicado: (2023)

Myo-Inositol and D-Chiro-Inositol as Modulators of Ovary Steroidogenesis: A Narrative Review
por: Bizzarri, Mariano, et al.
Publicado: (2023)

Anaerobic peroxisomes in Entamoeba histolytica metabolize myo-inositol
por: Verner, Zdeněk, et al.
Publicado: (2021)

Fluorination Influences the Bioisostery of Myo-Inositol Pyrophosphate Analogs
por: Hostachy, Sarah, et al.
Publicado: (2023)

Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart
por: Van Steenbergen, Anne, et al.
Publicado: (2017)

Marked oestrous cycle‐dependent regulation of rat arterial K(V)7.4 channels driven by GPER1
por: Baldwin, Samuel N., et al.
Publicado: (2022)

Inositol-phosphodihydroceramides in the periodontal pathogen Tannerella forsythia: Structural analysis and incorporation of exogenous myo-inositol
por: Megson, Zoë Anne, et al.
Publicado: (2015)

Effects of Inositol Hexaphosphate and Myo-Inositol Administration in Breast Cancer Patients during Adjuvant Chemotherapy
por: Amabile, Maria Ida, et al.
Publicado: (2021)

Lactic Acid and Thermal Treatments Trigger the Hydrolysis of Myo-Inositol Hexakisphosphate and Modify the Abundance of Lower Myo-Inositol Phosphates in Barley (Hordeum vulgare L.)
por: Metzler-Zebeli, Barbara U., et al.
Publicado: (2014)

Evaluation of expression and function of the H(+)/myo-inositol transporter HMIT
por: Di Daniel, Elena, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_quno1nb76lmlfkta5jne70boda