Age-Related Decline in Expression of Molecular Chaperones Induces Endoplasmic Reticulum Stress and Chondrocyte Apoptosis in Articular Cartilage

Aging is a major risk factor for the development of osteoarthritis (OA). One hallmark of aging is loss of proteostasis resulting in increased cellular stress and cell death. However, its effect on the development of OA is not clear. Here, using knee articular cartilage tissue from young and old cyno...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Li, Register, Thomas C, Yammani, Raghunatha R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2020
Materias:
Orginal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505268/
https://www.ncbi.nlm.nih.gov/pubmed/33014525
http://dx.doi.org/10.14336/AD.2019.1130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505268/
https://www.ncbi.nlm.nih.gov/pubmed/33014525
http://dx.doi.org/10.14336/AD.2019.1130

Ejemplares similares