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Sources of variation in cell-type RNA-Seq profiles
Cell-type specific gene expression profiles are needed for many computational methods operating on bulk RNA-Seq samples, such as deconvolution of cell-type fractions and digital cytometry. However, the gene expression profile of a cell type can vary substantially due to both technical factors and bi...
Autores principales: | Gustafsson, Johan, Held, Felix, Robinson, Jonathan L., Björnson, Elias, Jörnsten, Rebecka, Nielsen, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505444/ https://www.ncbi.nlm.nih.gov/pubmed/32956417 http://dx.doi.org/10.1371/journal.pone.0239495 |
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