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The Negative Cross-Talk between SAG/RBX2/ROC2 and APC/C E3 Ligases in Regulation of Cell Cycle Progression and Drug Resistance

Anaphase-promoting complex/cyclosome (APC/C) is a well-characterized E3 ligase that couples with UBE2C and UBE2S E2s for substrate ubiquitylation by the K11 linkage. Our recent data show that SAG/RBX2/ROC2, a RING component of Cullin-RING E3 ligase, also complexes with these E2s for K11-linked subst...

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Detalles Bibliográficos
Autores principales:	Zhang, Shizhen, Shen, Yanwen, Li, Hua, Bi, Chao, Sun, Yilun, Xiong, Xiufang, Wei, Wenyi, Sun, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505520/ https://www.ncbi.nlm.nih.gov/pubmed/32905768 http://dx.doi.org/10.1016/j.celrep.2020.108102

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