Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium

Neurological complications are common in patients with COVID-19. Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal pathogen of COVID-19, has been detected in some patient brains, its ability to infect brain cells and impact their function is not well understood. Here,...

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Detalles Bibliográficos
Autores principales: Jacob, Fadi, Pather, Sarshan R., Huang, Wei-Kai, Zhang, Feng, Wong, Samuel Zheng Hao, Zhou, Haowen, Cubitt, Beatrice, Fan, Wenqiang, Chen, Catherine Z., Xu, Miao, Pradhan, Manisha, Zhang, Daniel Y., Zheng, Wei, Bang, Anne G., Song, Hongjun, Carlos de la Torre, Juan, Ming, Guo-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505550/
https://www.ncbi.nlm.nih.gov/pubmed/33010822
http://dx.doi.org/10.1016/j.stem.2020.09.016

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