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Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif

Predicting gene expression from DNA sequence remains a major goal in the field of gene regulation. A challenge to this goal is the connectivity of the network, whose role in altering gene expression remains unclear. Here, we study a common autoregulatory network motif, the negative single-input modu...

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Detalles Bibliográficos
Autores principales: Ali, Md Zulfikar, Parisutham, Vinuselvi, Choubey, Sandeep, Brewster, Robert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505660/
https://www.ncbi.nlm.nih.gov/pubmed/32808926
http://dx.doi.org/10.7554/eLife.56517