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Targeting Toll-like receptor 4 with CLI-095 (TAK-242) enhances the antimetastatic effect of the estrogen receptor antagonist fulvestrant on non-small cell lung cancer

PURPOSE: Estrogen plays a critical role in the invasiveness and metastasis of non-small cell lung cancer (NSCLC) through estrogen receptor β (ERβ). However, the antimetastatic effect of the ERβ antagonist fulvestrant was still limited in NSCLC patients. Recently, Toll-like receptor 4 (TLR4) signalin...

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Detalles Bibliográficos
Autores principales: Fan, S., Liao, Y., Qiu, W., Li, L., Li, D., Cao, X., Ai, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505887/
https://www.ncbi.nlm.nih.gov/pubmed/32367494
http://dx.doi.org/10.1007/s12094-020-02353-3

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