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Structure-Guided Designing and Evaluation of Peptides Targeting Bacterial Transcription

The mycobacterial RNA polymerase (RNAP) is an essential and validated drug target for developing antibacterial drugs. The β-subunit of Mycobacterium tuberculosis (Mtb) RNAP (RpoB) interacts with an essential and global transcription factor, CarD, and confers antibiotic and oxidative stress resistanc...

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Detalles Bibliográficos
Autores principales:	Kaur, Gundeep, Kapoor, Srajan, Kaundal, Soni, Dutta, Dipak, Thakur, Krishan Gopal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505949/ https://www.ncbi.nlm.nih.gov/pubmed/33014990 http://dx.doi.org/10.3389/fbioe.2020.00797

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