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Chromatin and Transcriptional Response to Loss of TBX1 in Early Differentiation of Mouse Cells
The T-box transcription factor TBX1 has critical roles in the cardiopharyngeal lineage and the gene is haploinsufficient in DiGeorge syndrome, a typical developmental anomaly of the pharyngeal apparatus. Despite almost two decades of research, if and how TBX1 function triggers chromatin remodeling i...
Autores principales: | Cirino, Andrea, Aurigemma, Ilaria, Franzese, Monica, Lania, Gabriella, Righelli, Dario, Ferrentino, Rosa, Illingworth, Elizabeth, Angelini, Claudia, Baldini, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505952/ https://www.ncbi.nlm.nih.gov/pubmed/33015063 http://dx.doi.org/10.3389/fcell.2020.571501 |
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