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Preparation of a whole cell catalyst overexpressing acetohydroxyacid synthase of Thermotoga maritima and its application in the syntheses of α-hydroxyketones

The large catalytic subunit of acetohydroxyacid synthase (AHAS, EC 2.2.1.6) of Thermotoga maritima (TmcAHAS) was prepared in this study. It possesses high specific activity and excellent stability. The protein and a whole cell catalyst overexpressing the protein were applied to the preparation of α-...

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Detalles Bibliográficos
Autores principales: Liang, Yan-Fei, Yan, Le-Tian, Yue, Qiao, Zhao, Ji-Kui, Luo, Cai-Yun, Gao, Feng, Li, Heng, Gao, Wen-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505981/
https://www.ncbi.nlm.nih.gov/pubmed/32958806
http://dx.doi.org/10.1038/s41598-020-72416-6