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PKM2–c-Myc–Survivin Cascade Regulates the Cell Proliferation, Migration, and Tamoxifen Resistance in Breast Cancer

The M2 isoform of pyruvate kinase (PKM2), as a key glycolytic enzyme, plays important roles in tumorigenesis and chemotherapeutic drug resistance. However, the intricate mechanism of PKM2 as a protein kinase regulating breast cancer progression and tamoxifen resistance needs to be further clarified....

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Detalles Bibliográficos
Autores principales:	Yu, Pian, Li, Ao-xue, Chen, Xi-sha, Tian, Min, Wang, Hai-yan, Wang, Xin-luan, Zhang, Yi, Wang, Kuan-song, Cheng, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506054/ https://www.ncbi.nlm.nih.gov/pubmed/33013387 http://dx.doi.org/10.3389/fphar.2020.550469

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