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Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis

Liver ischemia-reperfusion injury (IRI) is a common clinical event with high morbidity in patients undergoing complex liver surgery or having abdominal trauma. Inflammatory and oxidative stress responses are the main contributing factors in liver IRI. The iridoid glucoside aucubin (AU) has good anti...

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Detalles Bibliográficos
Autores principales: Zhang, Shilong, Feng, Zanjie, Gao, Weidong, Duan, Yuling, Fan, Guoxin, Geng, Xin, Wu, Bo, Li, Kai, Liu, Kangwei, Peng, Cijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506056/
https://www.ncbi.nlm.nih.gov/pubmed/33013386
http://dx.doi.org/10.3389/fphar.2020.544124