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Evaluation of the clinical efficacy of a TW3-based fully automated bone age assessment system using deep neural networks
PURPOSE: The aim of this study was to evaluate the clinical efficacy of a Tanner-Whitehouse 3 (TW3)-based fully automated bone age assessment system on hand-wrist radiographs of Korean children and adolescents. MATERIALS AND METHODS: Hand-wrist radiographs of 80 subjects (40 boys and 40 girls, 7–15...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Academy of Oral and Maxillofacial Radiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506088/ https://www.ncbi.nlm.nih.gov/pubmed/33005581 http://dx.doi.org/10.5624/isd.2020.50.3.237 |
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author | Shin, Nan-Young Lee, Byoung-Dai Kang, Ju-Hee Kim, Hye-Rin Oh, Dong Hyo Lee, Byung Il Kim, Sung Hyun Lee, Mu Sook Heo, Min-Suk |
author_facet | Shin, Nan-Young Lee, Byoung-Dai Kang, Ju-Hee Kim, Hye-Rin Oh, Dong Hyo Lee, Byung Il Kim, Sung Hyun Lee, Mu Sook Heo, Min-Suk |
author_sort | Shin, Nan-Young |
collection | PubMed |
description | PURPOSE: The aim of this study was to evaluate the clinical efficacy of a Tanner-Whitehouse 3 (TW3)-based fully automated bone age assessment system on hand-wrist radiographs of Korean children and adolescents. MATERIALS AND METHODS: Hand-wrist radiographs of 80 subjects (40 boys and 40 girls, 7–15 years of age) were collected. The clinical efficacy was evaluated by comparing the bone ages that were determined using the system with those from the reference standard produced by 2 oral and maxillofacial radiologists. Comparisons were conducted using the paired t-test and simple regression analysis. RESULTS: The bone ages estimated with this bone age assessment system were not significantly different from those obtained with the reference standard (P>0.05) and satisfied the equivalence criterion of 0.6 years within the 95% confidence interval (− 0.07 to 0.22), demonstrating excellent performance of the system. Similarly, in the comparisons of gender subgroups, no significant difference in bone age between the values produced by the system and the reference standard was observed (P>0.05 for both boys and girls). The determination coefficients obtained via regression analysis were 0.962, 0.945, and 0.952 for boys, girls, and overall, respectively (P=0.000); hence, the radiologist-determined bone ages and the system-determined bone ages were strongly correlated. CONCLUSION: This TW3-based system can be effectively used for bone age assessment based on hand-wrist radiographs of Korean children and adolescents. |
format | Online Article Text |
id | pubmed-7506088 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Korean Academy of Oral and Maxillofacial Radiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-75060882020-09-30 Evaluation of the clinical efficacy of a TW3-based fully automated bone age assessment system using deep neural networks Shin, Nan-Young Lee, Byoung-Dai Kang, Ju-Hee Kim, Hye-Rin Oh, Dong Hyo Lee, Byung Il Kim, Sung Hyun Lee, Mu Sook Heo, Min-Suk Imaging Sci Dent Original Article PURPOSE: The aim of this study was to evaluate the clinical efficacy of a Tanner-Whitehouse 3 (TW3)-based fully automated bone age assessment system on hand-wrist radiographs of Korean children and adolescents. MATERIALS AND METHODS: Hand-wrist radiographs of 80 subjects (40 boys and 40 girls, 7–15 years of age) were collected. The clinical efficacy was evaluated by comparing the bone ages that were determined using the system with those from the reference standard produced by 2 oral and maxillofacial radiologists. Comparisons were conducted using the paired t-test and simple regression analysis. RESULTS: The bone ages estimated with this bone age assessment system were not significantly different from those obtained with the reference standard (P>0.05) and satisfied the equivalence criterion of 0.6 years within the 95% confidence interval (− 0.07 to 0.22), demonstrating excellent performance of the system. Similarly, in the comparisons of gender subgroups, no significant difference in bone age between the values produced by the system and the reference standard was observed (P>0.05 for both boys and girls). The determination coefficients obtained via regression analysis were 0.962, 0.945, and 0.952 for boys, girls, and overall, respectively (P=0.000); hence, the radiologist-determined bone ages and the system-determined bone ages were strongly correlated. CONCLUSION: This TW3-based system can be effectively used for bone age assessment based on hand-wrist radiographs of Korean children and adolescents. Korean Academy of Oral and Maxillofacial Radiology 2020-09 2020-09-16 /pmc/articles/PMC7506088/ /pubmed/33005581 http://dx.doi.org/10.5624/isd.2020.50.3.237 Text en Copyright © 2020 by Korean Academy of Oral and Maxillofacial Radiology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Shin, Nan-Young Lee, Byoung-Dai Kang, Ju-Hee Kim, Hye-Rin Oh, Dong Hyo Lee, Byung Il Kim, Sung Hyun Lee, Mu Sook Heo, Min-Suk Evaluation of the clinical efficacy of a TW3-based fully automated bone age assessment system using deep neural networks |
title | Evaluation of the clinical efficacy of a TW3-based fully automated bone age assessment system using deep neural networks |
title_full | Evaluation of the clinical efficacy of a TW3-based fully automated bone age assessment system using deep neural networks |
title_fullStr | Evaluation of the clinical efficacy of a TW3-based fully automated bone age assessment system using deep neural networks |
title_full_unstemmed | Evaluation of the clinical efficacy of a TW3-based fully automated bone age assessment system using deep neural networks |
title_short | Evaluation of the clinical efficacy of a TW3-based fully automated bone age assessment system using deep neural networks |
title_sort | evaluation of the clinical efficacy of a tw3-based fully automated bone age assessment system using deep neural networks |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506088/ https://www.ncbi.nlm.nih.gov/pubmed/33005581 http://dx.doi.org/10.5624/isd.2020.50.3.237 |
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