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Intravenous Administration of Pyroglutamyl Apelin-13 Alleviates Murine Inflammatory Pain via the Kappa Opioid Receptor

Apelin is an endogenous neuropeptide, which has wide distribution in central nervous system and peripheral tissues. Pyroglutamyl apelin-13 [(pyr)apelin-13] is the major apelin isoform in human plasma. However, the role of peripheral (pyr)apelin-13 in pain regulation is unknown. The aim of this study...

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Detalles Bibliográficos
Autores principales:	Lv, Shuangyu, Zhang, Xiaomei, Feng, Yu, Zhou, Yuchen, Cui, Binbin, Yang, Yanjie, Wang, Xinchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506098/ https://www.ncbi.nlm.nih.gov/pubmed/33013308 http://dx.doi.org/10.3389/fnins.2020.00929

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