Selective Phosphodiesterase 1 Inhibitor BTTQ Reduces Blood Pressure in Spontaneously Hypertensive and Dahl Salt Sensitive Rats: Role of Peripheral Vasodilation

Regulation of the peripheral vascular resistance via modulating the vessel diameter has been considered as a main determinant of the arterial blood pressure. Phosphodiesterase enzymes (PDE1-11) hydrolyse cyclic nucleotides, which are key players controlling the vessel diameter and, thus, peripheral...

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Detalles Bibliográficos
Autores principales: Dey, Asim B., Khedr, Sherif, Bean, James, Porras, Leah L., Meredith, Tamika D., Willard, Francis S., Hass, Joseph V., Zhou, Xin, Terashvili, Maia, Jesudason, Cynthia D., Ruley, Kevin M., Wiley, Michael R., Kowala, Mark, Atkinson, Simon J., Staruschenko, Alexander, Rekhter, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506137/
https://www.ncbi.nlm.nih.gov/pubmed/33013477
http://dx.doi.org/10.3389/fphys.2020.543727

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