A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus

Eosinophilic pustular folliculitis (EPF) (Ofuji disease) is a chronic, noninfectious pruritic cutaneous disorder of unknown etiology. No official guidelines are available for its treatment. Herein we present the case of a 59-year-old Caucasian man admitted to our outpatient clinic due to a generaliz...

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Autores principales: Marasca, Claudio, Ruggiero, Angelo, Fabbrocini, Gabriella, Megna, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2020
Materias:
Single Case
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506242/
https://www.ncbi.nlm.nih.gov/pubmed/32999652
http://dx.doi.org/10.1159/000509176
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author Marasca, Claudio
Ruggiero, Angelo
Fabbrocini, Gabriella
Megna, Matteo
author_facet Marasca, Claudio
Ruggiero, Angelo
Fabbrocini, Gabriella
Megna, Matteo
author_sort Marasca, Claudio
collection PubMed
description Eosinophilic pustular folliculitis (EPF) (Ofuji disease) is a chronic, noninfectious pruritic cutaneous disorder of unknown etiology. No official guidelines are available for its treatment. Herein we present the case of a 59-year-old Caucasian man admitted to our outpatient clinic due to a generalized itchy skin rash characterized by papulo-pustules involving the face, trunk, and limbs. Histological examination supported the clinical diagnosis of EPF (Ofuji disease). The combination of low-dose oral indomethacin and topical tacrolimus ointment once a day led to a complete resolution of the lesions as well as associated symptoms in 8 weeks.
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spelling pubmed-75062422020-09-29 A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus Marasca, Claudio Ruggiero, Angelo Fabbrocini, Gabriella Megna, Matteo Case Rep Dermatol Single Case Eosinophilic pustular folliculitis (EPF) (Ofuji disease) is a chronic, noninfectious pruritic cutaneous disorder of unknown etiology. No official guidelines are available for its treatment. Herein we present the case of a 59-year-old Caucasian man admitted to our outpatient clinic due to a generalized itchy skin rash characterized by papulo-pustules involving the face, trunk, and limbs. Histological examination supported the clinical diagnosis of EPF (Ofuji disease). The combination of low-dose oral indomethacin and topical tacrolimus ointment once a day led to a complete resolution of the lesions as well as associated symptoms in 8 weeks. S. Karger AG 2020-08-18 /pmc/articles/PMC7506242/ /pubmed/32999652 http://dx.doi.org/10.1159/000509176 Text en Copyright © 2020 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Marasca, Claudio
Ruggiero, Angelo
Fabbrocini, Gabriella
Megna, Matteo
A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus
title A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus
title_full A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus
title_fullStr A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus
title_full_unstemmed A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus
title_short A Case of Ofuji Disease Successfully Treated with the Combination of Low-Dose Indomethacin and Topical Tacrolimus
title_sort case of ofuji disease successfully treated with the combination of low-dose indomethacin and topical tacrolimus
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506242/
https://www.ncbi.nlm.nih.gov/pubmed/32999652
http://dx.doi.org/10.1159/000509176
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