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Rapid Improvement of the Performance Status and Reduction of the Tumor Size in KRAS-Mutated Colorectal Cancer Patient Receiving Binimetinib, Hydroxychloroquine, and Bevacizumab
Activating RAS mutations occur in more than a half of colorectal cancers (CRCs). RAS-mutated CRCs are notoriously difficult to treat given that they are characterized by the aggressive disease course and the lack of appropriate targeted therapies. Recent preclinical studies demonstrated that RAS-mut...
Autores principales: | Orlov, Sergey V., Urtenova, Magaripa A., Sviridenko, Maria A., Nesterov, Denis V., Sokolova, Tatiana N., Imyanitov, Evgeny N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506371/ https://www.ncbi.nlm.nih.gov/pubmed/32999660 http://dx.doi.org/10.1159/000509241 |
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