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Structure and function of bacteriophage CBA120 ORF211 (TSP2), the determinant of phage specificity towards E. coli O157:H7

The genome of Escherichia coli O157:H7 bacteriophage vB_EcoM_CBA120 encodes four distinct tailspike proteins (TSPs). The four TSPs, TSP1-4, attach to the phage baseplate forming a branched structure. We report the 1.9 Å resolution crystal structure of TSP2 (ORF211), the TSP that confers phage specif...

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Detalles Bibliográficos
Autores principales:	Greenfield, Julia, Shang, Xiaoran, Luo, Heng, Zhou, Yan, Linden, Sara B., Heselpoth, Ryan D., Leiman, Petr G., Nelson, Daniel C., Herzberg, Osnat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506556/ https://www.ncbi.nlm.nih.gov/pubmed/32958885 http://dx.doi.org/10.1038/s41598-020-72373-0

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