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Physical Validation of a Residual Impedance Rejection Method during Ultra-Low Frequency Bio-Impedance Spectral Measurements

Accurate and reliable measurement of the electrical impedance spectrum is an essential requirement in order to draw relevant conclusions in many fields and a variety of applications; in particular, for biological processes. Even in the state-of-the-art methods developed for this purpose, the accurac...

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Autores principales: Vizvari, Zoltan, Gyorfi, Nina, Odry, Akos, Sari, Zoltan, Klincsik, Mihaly, Gergics, Marin, Kovacs, Levente, Kovacs, Anita, Pal, Jozsef, Karadi, Zoltan, Odry, Peter, Toth, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506680/
https://www.ncbi.nlm.nih.gov/pubmed/32825145
http://dx.doi.org/10.3390/s20174686
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author Vizvari, Zoltan
Gyorfi, Nina
Odry, Akos
Sari, Zoltan
Klincsik, Mihaly
Gergics, Marin
Kovacs, Levente
Kovacs, Anita
Pal, Jozsef
Karadi, Zoltan
Odry, Peter
Toth, Attila
author_facet Vizvari, Zoltan
Gyorfi, Nina
Odry, Akos
Sari, Zoltan
Klincsik, Mihaly
Gergics, Marin
Kovacs, Levente
Kovacs, Anita
Pal, Jozsef
Karadi, Zoltan
Odry, Peter
Toth, Attila
author_sort Vizvari, Zoltan
collection PubMed
description Accurate and reliable measurement of the electrical impedance spectrum is an essential requirement in order to draw relevant conclusions in many fields and a variety of applications; in particular, for biological processes. Even in the state-of-the-art methods developed for this purpose, the accuracy and efficacy of impedance measurements are reduced in biological systems, due to the regular occurrence of parameters causing measurement errors such as residual impedance, parasitic capacitance, generator anomalies, and so on. Recent observations have reported the necessity of decreasing such inaccuracies whenever measurements are performed in the ultra-low frequency range, as the above-mentioned errors are almost entirely absent in such cases. The current research work proposes a method which can reject the anomalies listed above when measuring in the ultra-low frequency range, facilitating data collection at the same time. To demonstrate our hypothesis, originating from the consideration of the determinant role of the measuring frequency, a physical model is proposed to examine the effectiveness of our method by measuring across the commonly used vs. ultra-low frequency ranges. Validation measurements reflect that the range of frequencies and the accuracy is much greater than in state-of-the-art methods. Using the proposed new impedance examination technique, biological system characterization can be carried out more accurately.
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spelling pubmed-75066802020-09-26 Physical Validation of a Residual Impedance Rejection Method during Ultra-Low Frequency Bio-Impedance Spectral Measurements Vizvari, Zoltan Gyorfi, Nina Odry, Akos Sari, Zoltan Klincsik, Mihaly Gergics, Marin Kovacs, Levente Kovacs, Anita Pal, Jozsef Karadi, Zoltan Odry, Peter Toth, Attila Sensors (Basel) Article Accurate and reliable measurement of the electrical impedance spectrum is an essential requirement in order to draw relevant conclusions in many fields and a variety of applications; in particular, for biological processes. Even in the state-of-the-art methods developed for this purpose, the accuracy and efficacy of impedance measurements are reduced in biological systems, due to the regular occurrence of parameters causing measurement errors such as residual impedance, parasitic capacitance, generator anomalies, and so on. Recent observations have reported the necessity of decreasing such inaccuracies whenever measurements are performed in the ultra-low frequency range, as the above-mentioned errors are almost entirely absent in such cases. The current research work proposes a method which can reject the anomalies listed above when measuring in the ultra-low frequency range, facilitating data collection at the same time. To demonstrate our hypothesis, originating from the consideration of the determinant role of the measuring frequency, a physical model is proposed to examine the effectiveness of our method by measuring across the commonly used vs. ultra-low frequency ranges. Validation measurements reflect that the range of frequencies and the accuracy is much greater than in state-of-the-art methods. Using the proposed new impedance examination technique, biological system characterization can be carried out more accurately. MDPI 2020-08-19 /pmc/articles/PMC7506680/ /pubmed/32825145 http://dx.doi.org/10.3390/s20174686 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vizvari, Zoltan
Gyorfi, Nina
Odry, Akos
Sari, Zoltan
Klincsik, Mihaly
Gergics, Marin
Kovacs, Levente
Kovacs, Anita
Pal, Jozsef
Karadi, Zoltan
Odry, Peter
Toth, Attila
Physical Validation of a Residual Impedance Rejection Method during Ultra-Low Frequency Bio-Impedance Spectral Measurements
title Physical Validation of a Residual Impedance Rejection Method during Ultra-Low Frequency Bio-Impedance Spectral Measurements
title_full Physical Validation of a Residual Impedance Rejection Method during Ultra-Low Frequency Bio-Impedance Spectral Measurements
title_fullStr Physical Validation of a Residual Impedance Rejection Method during Ultra-Low Frequency Bio-Impedance Spectral Measurements
title_full_unstemmed Physical Validation of a Residual Impedance Rejection Method during Ultra-Low Frequency Bio-Impedance Spectral Measurements
title_short Physical Validation of a Residual Impedance Rejection Method during Ultra-Low Frequency Bio-Impedance Spectral Measurements
title_sort physical validation of a residual impedance rejection method during ultra-low frequency bio-impedance spectral measurements
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506680/
https://www.ncbi.nlm.nih.gov/pubmed/32825145
http://dx.doi.org/10.3390/s20174686
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