Cargando…

Inflammatory phenotyping predicts clinical outcome in COVID-19

BACKGROUND: The COVID-19 pandemic has led to more than 760,000 deaths worldwide (correct as of 16th August 2020). Studies suggest a hyperinflammatory response is a major cause of disease severity and death. Identitfying COVID-19 patients with hyperinflammation may identify subgroups who could benefi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Burke, H., Freeman, A., Cellura, D. C., Stuart, B. L., Brendish, N. J., Poole, S., Borca, F., Phan, H. T. T., Sheard, N., Williams, S., Spalluto, C. M., Staples, K. J., Clark, T. W., Wilkinson, T. M. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506817/ https://www.ncbi.nlm.nih.gov/pubmed/32962703 http://dx.doi.org/10.1186/s12931-020-01511-z

Ejemplares similares

Pulmonary EV miRNA profiles identify disease and distinct inflammatory endotypes in COPD
por: Burke, Hannah, et al.
Publicado: (2022)

SARS-CoV-2 viral load at presentation to hospital is independently associated with the risk of death
por: Tanner, Alex R, et al.
Publicado: (2021)

Dysregulation of COVID-19 related gene expression in the COPD lung
por: Watson, Alastair, et al.
Publicado: (2021)

Acquired immune responses to the seasonal trivalent influenza vaccination in COPD
por: Staples, K. J., et al.
Publicado: (2019)

Re: 'Syndromic panels or “panel syndrome”? A perspective through the lens of respiratory-tract infections' by Zanella et al
por: Brendish, N.J., et al.
Publicado: (2020)

Exercise Training Induces a Shift in Extracellular Redox Status with Alterations in the Pulmonary and Systemic Redox Landscape in Asthma
por: Freeman, Anna, et al.
Publicado: (2021)

Research Evaluation Alongside Clinical Treatment in COVID-19 (REACT COVID-19): an observational and biobanking study
por: Burke, Hannah, et al.
Publicado: (2021)

Clinical characteristics, symptoms and outcomes of 1054 adults presenting to hospital with suspected COVID-19: A comparison of patients with and without SARS-CoV-2 infection
por: Brendish, Nathan J, et al.
Publicado: (2020)

Risk factors for persistent abnormality on chest radiographs at 12-weeks post hospitalisation with PCR confirmed COVID-19
por: Wallis, T. J. M., et al.
Publicado: (2021)

Influence of Hypoxia on the Epithelial-Pathogen Interactions in the Lung: Implications for Respiratory Disease
por: Page, Lee K., et al.
Publicado: (2021)

The Role of Non-Typeable Haemophilus influenzae Biofilms in Chronic Obstructive Pulmonary Disease
por: Weeks, Jake R., et al.
Publicado: (2021)

The Role of Extracellular Vesicles as a Shared Disease Mechanism Contributing to Multimorbidity in Patients With COPD
por: Reid, Laura V., et al.
Publicado: (2021)

Routine molecular point-of-care testing for SARS-CoV-2 reduces hospital-acquired COVID-19
por: Livingstone, Robert, et al.
Publicado: (2022)

FebriDx host response point-of-care testing improves patient triage for coronavirus disease 2019 (COVID-19) in the emergency department
por: Mansbridge, Christopher T., et al.
Publicado: (2022)

FebriDx host response point-of-care testing improves patient triage for coronavirus disease 2019 (COVID-19) in the emergency department – ADDENDUM
por: Mansbridge, Christopher T., et al.
Publicado: (2022)

SARS-CoV-2 has displaced other seasonal respiratory viruses: Results from a prospective cohort study
por: Poole, Stephen, et al.
Publicado: (2020)

Biomarker identification using dynamic time warping analysis: a longitudinal cohort study of patients with COVID-19 in a UK tertiary hospital
por: Burke, Hannah, et al.
Publicado: (2022)

Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital (COV-19POC): a prospective, interventional, non-randomised, controlled study
por: Brendish, Nathan J, et al.
Publicado: (2020)

Physical distancing in schools for SARS-CoV-2 and the resurgence of rhinovirus
por: Poole, Stephen, et al.
Publicado: (2020)

Increase in circulation of non-SARS-CoV-2 respiratory viruses following easing of social distancing is associated with increasing hospital attendance
por: Tanner, Alex R, et al.
Publicado: (2021)

Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD
por: Hristova, Ventzislava A., et al.
Publicado: (2022)

Novel expression of a functional trimeric fragment of human SP-A with efficacy in neutralisation of RSV
por: Watson, Alastair, et al.
Publicado: (2017)

654. Evaluation of the Febridx Host Response Point-of-Care Test to Differentiate Viral From Bacterial Etiology in Adults Hospitalized with Acute Respiratory Illness During Influenza Season
por: Beard, Kate, et al.
Publicado: (2019)

Defining a role for exercise training in the management of asthma
por: Freeman, Anna T., et al.
Publicado: (2020)

Viral Infection of Human Lung Macrophages Increases PDL1 Expression via IFNβ
por: Staples, Karl J., et al.
Publicado: (2015)

Pragmatic multicentre randomised controlled trial evaluating the impact of a routine molecular point-of-care ‘test-and-treat’ strategy for influenza in adults hospitalised with acute respiratory illness (FluPOC): trial protocol
por: Beard, Kate, et al.
Publicado: (2019)

Relationship of CT-quantified emphysema, small airways disease and bronchial wall dimensions with physiological, inflammatory and infective measures in COPD
por: Ostridge, Kristoffer, et al.
Publicado: (2018)

Molecular point-of-care testing for respiratory viruses versus routine clinical care in adults with acute respiratory illness presenting to secondary care: a pragmatic randomised controlled trial protocol (ResPOC)
por: Brendish, Nathan J., et al.
Publicado: (2017)

Point-of-care testing for respiratory viruses in adults: The current landscape and future potential
por: Brendish, Nathan J., et al.
Publicado: (2015)

Diagnostic accuracy of the FebriDx host response point-of-care test in patients hospitalised with suspected COVID-19
por: Clark, Tristan W., et al.
Publicado: (2020)

2796. The Impact of Syndromic Molecular Point-of-Care Testing for Respiratory Viruses on Antibiotic Use in Adults Presenting to Hospital with Exacerbation of Airways Disease: Further Analysis From a Randomized Controlled Trial
por: Clark, Tristan William, et al.
Publicado: (2019)

Wave comparisons of clinical characteristics and outcomes of COVID-19 admissions - Exploring the impact of treatment and strain dynamics
por: Freeman, Anna, et al.
Publicado: (2022)

Impact of point-of-care testing for respiratory viruses on antibiotic use in adults with exacerbation of airways disease
por: Brendish, Nathan J., et al.
Publicado: (2019)

1717. The Impact of Routine Molecular Point-of-care Testing for Gastrointestinal Pathogens in Adults Hospitalized With Suspected Gastroenteritis: Results of a Pragmatic Randomized Controlled Trial (GastroPOC)
por: Malachira, Ahalya, et al.
Publicado: (2018)

Genetic Risk Scores Identify Genetic Aetiology of Inflammatory Bowel Disease Phenotypes
por: Voskuil, M D, et al.
Publicado: (2020)

120. Impact of a Molecular Point-of-care ‘test and Treat’ Strategy for Influenza in Hospitalised adults: A Multi-centre, Randomised Controlled Trial (FluPOC)
por: Clark, Tristan William, et al.
Publicado: (2020)

Visualization of the inflammatory response to injury by neutrophil phenotype categories: Neutrophil phenotypes after trauma
por: de Fraiture, Emma J., et al.
Publicado: (2022)

Influenza vaccination: protecting the most vulnerable
por: Tanner, Alex R., et al.
Publicado: (2021)

Combined RT-PCR and Host Response Point-of-Care Testing in Patients Hospitalised with Suspected COVID-19: A Prospective Diagnostic Accuracy Study
por: Brendish, Nathan J., et al.
Publicado: (2022)

Airway Epithelial Cells Drive Airway Smooth Muscle Cell Phenotype Switching to the Proliferative and Pro-inflammatory Phenotype
por: O’Sullivan, M. J., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2v7tirpu4aivd8i69cllqia5df