An Acridine-Based Fluorescent Sensor for Monitoring ClO(−) in Water Samples and Zebrafish

A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO(−) was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed n...

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Detalles Bibliográficos
Autores principales: Lee, Su Chan, Park, Soyoung, So, Haeri, Lee, Gyudong, Kim, Ki-Tae, Kim, Cheal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506904/
https://www.ncbi.nlm.nih.gov/pubmed/32842534
http://dx.doi.org/10.3390/s20174764
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author Lee, Su Chan
Park, Soyoung
So, Haeri
Lee, Gyudong
Kim, Ki-Tae
Kim, Cheal
author_facet Lee, Su Chan
Park, Soyoung
So, Haeri
Lee, Gyudong
Kim, Ki-Tae
Kim, Cheal
author_sort Lee, Su Chan
collection PubMed
description A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO(−) was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO(−) and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 μM. Additionally, BK was satisfactorily applied for sensing ClO(−) in water samples and zebrafish.
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spelling pubmed-75069042020-09-30 An Acridine-Based Fluorescent Sensor for Monitoring ClO(−) in Water Samples and Zebrafish Lee, Su Chan Park, Soyoung So, Haeri Lee, Gyudong Kim, Ki-Tae Kim, Cheal Sensors (Basel) Letter A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO(−) was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO(−) and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 μM. Additionally, BK was satisfactorily applied for sensing ClO(−) in water samples and zebrafish. MDPI 2020-08-23 /pmc/articles/PMC7506904/ /pubmed/32842534 http://dx.doi.org/10.3390/s20174764 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Letter
Lee, Su Chan
Park, Soyoung
So, Haeri
Lee, Gyudong
Kim, Ki-Tae
Kim, Cheal
An Acridine-Based Fluorescent Sensor for Monitoring ClO(−) in Water Samples and Zebrafish
title An Acridine-Based Fluorescent Sensor for Monitoring ClO(−) in Water Samples and Zebrafish
title_full An Acridine-Based Fluorescent Sensor for Monitoring ClO(−) in Water Samples and Zebrafish
title_fullStr An Acridine-Based Fluorescent Sensor for Monitoring ClO(−) in Water Samples and Zebrafish
title_full_unstemmed An Acridine-Based Fluorescent Sensor for Monitoring ClO(−) in Water Samples and Zebrafish
title_short An Acridine-Based Fluorescent Sensor for Monitoring ClO(−) in Water Samples and Zebrafish
title_sort acridine-based fluorescent sensor for monitoring clo(−) in water samples and zebrafish
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506904/
https://www.ncbi.nlm.nih.gov/pubmed/32842534
http://dx.doi.org/10.3390/s20174764
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