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Sequential Linkage of Carbohydrate Antigens to Mimic Capsular Polysaccharides: Toward Semisynthetic Glycoconjugate Vaccine Candidates against Streptococcus pneumoniae Serotype 14

[Image: see text] Vaccines based on isolated polysaccharides successfully protect humans from bacterial pathogens such as Streptococcus pneumoniae. Because polysaccharide production and isolation can be technically challenging, glycoconjugates containing synthetic antigens are an attractive alternat...

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Detalles Bibliográficos
Autores principales:	Seco, Bruna M. S., Xu, Fei-Fei, Grafmüller, Andrea, Kottari, Naresh, Pereira, Claney L., Seeberger, Peter H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506939/ https://www.ncbi.nlm.nih.gov/pubmed/32835479 http://dx.doi.org/10.1021/acschembio.0c00360

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