Saving patients with out‐of‐hospital cardiac arrest using Impella: three case reports

BACKGROUND: The efficacy of Impella for patients with out‐of‐hospital cardiac arrest is unknown. We report the cases of three patients with cardiogenic out‐of‐hospital cardiac arrest who received hemodynamic support with Impella. CASE PRESENTATION: Two patients, Case 2 and Case 3, received concomitant treatment with venoarterial extracorporeal membrane oxygenation and Impella. Percutaneous coronary intervention was undertaken in two patients, Case 1 and Case 3. Two patients, Case 1 and Case 3, showed favorable neurological function with the Glasgow–Pittsburgh cerebral performance and overall performance categories score of 1 at discharge. CONCLUSION: These findings suggest that Impella is effective in patients with out‐of‐hospital cardiac arrest. Further studies are required to understand the use of Impella for patients with out‐of‐hospital cardiac arrest.