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miR-149-5p inhibition reduces Alzheimer's disease β-amyloid generation in 293/APPsw cells by upregulating H4K16ac via KAT8

Alzheimer's disease (AD), the leading cause of age-related dementia, is characterized by abnormal β-amyloid accumulation. During learning, memory formation and consolidation, increased levels of histone H3 and H4 acetylation are observed. The present study reported significantly decreased level...

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Detalles Bibliográficos
Autores principales:	Chen, Fuyan, Chen, Huifeng, Jia, Yujie, Lu, Hai, Tan, Qiaorui, Zhou, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507054/ https://www.ncbi.nlm.nih.gov/pubmed/32973937 http://dx.doi.org/10.3892/etm.2020.9216

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