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p.P476S mutation of RBPJL inhibits the efficacy of anti‐PD‐1 therapy in oesophageal squamous cell carcinoma by blunting T‐cell responses
OBJECTIVES: Anti‐PD‐1 immune checkpoint blockade represents the onset of a new era in cancer immunotherapy. However, robust predictors are necessary for screening patients with immune checkpoint‐responsive oesophageal squamous cell carcinoma (ESCC). METHODS: We obtained biopsy samples from an ESCC p...
Autores principales: | Miao, Lei, Wei, Xiao‐Li, Zhao, Qi, Qi, JingJing, Ren, Chao, Wu, Qi‐Nian, Wei, Da‐Liang, Liu, Jia, Wang, Feng‐Hua, Xu, Rui‐Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507108/ https://www.ncbi.nlm.nih.gov/pubmed/32994998 http://dx.doi.org/10.1002/cti2.1172 |
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