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Characteristics and trends of childhood cancer in Pudong, China, 2002–2015

BACKGROUND: With the growing threat of cancer to children’s health, it is necessary to analyze characteristics and trends of childhood cancer to formulate better cancer prevention strategies. METHODS: Data on the 430 children with cancer during 2002–2015 were collected from the Pudong Cancer Registr...

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Autores principales: Ji, Junqi, Luo, Zheng, Chen, Yichen, Xu, Xiaoyun, Li, Xiaopan, Liu, Shijian, Tong, Shilu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507240/
https://www.ncbi.nlm.nih.gov/pubmed/32958056
http://dx.doi.org/10.1186/s12889-020-09493-9
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author Ji, Junqi
Luo, Zheng
Chen, Yichen
Xu, Xiaoyun
Li, Xiaopan
Liu, Shijian
Tong, Shilu
author_facet Ji, Junqi
Luo, Zheng
Chen, Yichen
Xu, Xiaoyun
Li, Xiaopan
Liu, Shijian
Tong, Shilu
author_sort Ji, Junqi
collection PubMed
description BACKGROUND: With the growing threat of cancer to children’s health, it is necessary to analyze characteristics and trends of childhood cancer to formulate better cancer prevention strategies. METHODS: Data on the 430 children with cancer during 2002–2015 were collected from the Pudong Cancer Registry, diagnosed with the International Classification of Diseases for Oncology and categorized according to the International Classification of Childhood Cancer. The incidence rate, trends over time, and survival of patients grouped by sex, age, and region were explored using the Kaplan-Meier, Cox regression, and Joinpoint Regression models. RESULTS: The crude childhood cancer incidence and world age-standardized incidence rate (ASR) were 115.1/1,000,000 and 116.3/1,000,000 person-years. The two most frequent cancers were leukemia (136/430, 31.63%, ASR, 37.8/1,000,000 person-years) and central nervous system (CNS) tumors (86/430, 20.00%, ASR, 22.9/1,000,000 person-years). Our findings indicate that the survival rate for children between 10 and 15 years of age was higher than that for 5–10; and the survival rate for children who had leukemia was higher than that of children with CNS tumors. However, the overall incidence of childhood cancer, and leukemia, CNS tumors remained relatively stable in Pudong between 2002 and 2015. CONCLUSIONS: The incidence and survival rate for childhood cancer patients varied by age and cancer type. The overall trends of childhood cancer incidence remained relatively stable in Pudong from 2002 to 2015 even though socioeconomic development has been unprecedentedly fast in this region.
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spelling pubmed-75072402020-09-23 Characteristics and trends of childhood cancer in Pudong, China, 2002–2015 Ji, Junqi Luo, Zheng Chen, Yichen Xu, Xiaoyun Li, Xiaopan Liu, Shijian Tong, Shilu BMC Public Health Research Article BACKGROUND: With the growing threat of cancer to children’s health, it is necessary to analyze characteristics and trends of childhood cancer to formulate better cancer prevention strategies. METHODS: Data on the 430 children with cancer during 2002–2015 were collected from the Pudong Cancer Registry, diagnosed with the International Classification of Diseases for Oncology and categorized according to the International Classification of Childhood Cancer. The incidence rate, trends over time, and survival of patients grouped by sex, age, and region were explored using the Kaplan-Meier, Cox regression, and Joinpoint Regression models. RESULTS: The crude childhood cancer incidence and world age-standardized incidence rate (ASR) were 115.1/1,000,000 and 116.3/1,000,000 person-years. The two most frequent cancers were leukemia (136/430, 31.63%, ASR, 37.8/1,000,000 person-years) and central nervous system (CNS) tumors (86/430, 20.00%, ASR, 22.9/1,000,000 person-years). Our findings indicate that the survival rate for children between 10 and 15 years of age was higher than that for 5–10; and the survival rate for children who had leukemia was higher than that of children with CNS tumors. However, the overall incidence of childhood cancer, and leukemia, CNS tumors remained relatively stable in Pudong between 2002 and 2015. CONCLUSIONS: The incidence and survival rate for childhood cancer patients varied by age and cancer type. The overall trends of childhood cancer incidence remained relatively stable in Pudong from 2002 to 2015 even though socioeconomic development has been unprecedentedly fast in this region. BioMed Central 2020-09-21 /pmc/articles/PMC7507240/ /pubmed/32958056 http://dx.doi.org/10.1186/s12889-020-09493-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Ji, Junqi
Luo, Zheng
Chen, Yichen
Xu, Xiaoyun
Li, Xiaopan
Liu, Shijian
Tong, Shilu
Characteristics and trends of childhood cancer in Pudong, China, 2002–2015
title Characteristics and trends of childhood cancer in Pudong, China, 2002–2015
title_full Characteristics and trends of childhood cancer in Pudong, China, 2002–2015
title_fullStr Characteristics and trends of childhood cancer in Pudong, China, 2002–2015
title_full_unstemmed Characteristics and trends of childhood cancer in Pudong, China, 2002–2015
title_short Characteristics and trends of childhood cancer in Pudong, China, 2002–2015
title_sort characteristics and trends of childhood cancer in pudong, china, 2002–2015
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507240/
https://www.ncbi.nlm.nih.gov/pubmed/32958056
http://dx.doi.org/10.1186/s12889-020-09493-9
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