Inhibition of Aurora Kinase B attenuates fibroblast activation and pulmonary fibrosis

Fibroblast activation including proliferation, survival, and ECM production is central to initiation and maintenance of fibrotic lesions in idiopathic pulmonary fibrosis (IPF). However, druggable molecules that target fibroblast activation remain limited. In this study, we show that multiple pro‐fib...

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Detalles Bibliográficos
Autores principales: Kasam, Rajesh K, Ghandikota, Sudhir, Soundararajan, Divyalakshmi, Reddy, Geereddy B, Huang, Steven K, Jegga, Anil G, Madala, Satish K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507328/
https://www.ncbi.nlm.nih.gov/pubmed/32761869
http://dx.doi.org/10.15252/emmm.202012131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507328/
https://www.ncbi.nlm.nih.gov/pubmed/32761869
http://dx.doi.org/10.15252/emmm.202012131

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