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Inhibition of Aurora Kinase B attenuates fibroblast activation and pulmonary fibrosis
Fibroblast activation including proliferation, survival, and ECM production is central to initiation and maintenance of fibrotic lesions in idiopathic pulmonary fibrosis (IPF). However, druggable molecules that target fibroblast activation remain limited. In this study, we show that multiple pro‐fib...
Autores principales: | Kasam, Rajesh K, Ghandikota, Sudhir, Soundararajan, Divyalakshmi, Reddy, Geereddy B, Huang, Steven K, Jegga, Anil G, Madala, Satish K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507328/ https://www.ncbi.nlm.nih.gov/pubmed/32761869 http://dx.doi.org/10.15252/emmm.202012131 |
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