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Energy needs in the treatment of uncomplicated severe acute malnutrition: Secondary analysis to optimize delivery of ready‐to‐use therapeutic foods

Outpatient therapeutic feeding protocols for the treatment of uncomplicated severe acute malnutrition in children were initially based on weight gain data from inpatient settings and expert knowledge of the physiological requirements during recovery. However, weight gain and energy requirements from...

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Autores principales: Isanaka, Sheila, Andersen, Christopher T., Hanson, Kerstin E., Berthé, Fatou, Grais, Rebecca F., Briend, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507348/
https://www.ncbi.nlm.nih.gov/pubmed/32144946
http://dx.doi.org/10.1111/mcn.12989
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author Isanaka, Sheila
Andersen, Christopher T.
Hanson, Kerstin E.
Berthé, Fatou
Grais, Rebecca F.
Briend, André
author_facet Isanaka, Sheila
Andersen, Christopher T.
Hanson, Kerstin E.
Berthé, Fatou
Grais, Rebecca F.
Briend, André
author_sort Isanaka, Sheila
collection PubMed
description Outpatient therapeutic feeding protocols for the treatment of uncomplicated severe acute malnutrition in children were initially based on weight gain data from inpatient settings and expert knowledge of the physiological requirements during recovery. However, weight gain and energy requirements from historic inpatient settings may differ from modern outpatient settings and therefore may not be appropriate to guide current therapeutic feeding protocols. We calculated the weight gain and average estimated total daily energy requirement of children successfully treated for uncomplicated severe acute malnutrition as outpatients in Niger (n = 790). Mean energy provided by six therapeutic feeding protocols was calculated and compared with average estimated energy requirements in the study population. Overall weight gain was 5.5 g·kg(−1)·day(−1) among recovered children. Average energy requirements ranged from 92 to 110 kcal·kg(−1)·day(−1) depending on the estimation approach. Two current therapeutic feeding protocols were found to provide an excess of energy after the first week of treatment in our study population, whereas four research protocols tended to provide less energy than the estimated requirement after the first week of treatment. Alternative feeding protocols have the potential to simplify and lead to important savings for programmes but should be evaluated to show adequacy to meet the energy needs of children under treatment, as well as feasibility and cost efficiency. Our findings rely on theoretical calculations based on several assumptions and should be confirmed in field studies.
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spelling pubmed-75073482020-09-28 Energy needs in the treatment of uncomplicated severe acute malnutrition: Secondary analysis to optimize delivery of ready‐to‐use therapeutic foods Isanaka, Sheila Andersen, Christopher T. Hanson, Kerstin E. Berthé, Fatou Grais, Rebecca F. Briend, André Matern Child Nutr Original Articles Outpatient therapeutic feeding protocols for the treatment of uncomplicated severe acute malnutrition in children were initially based on weight gain data from inpatient settings and expert knowledge of the physiological requirements during recovery. However, weight gain and energy requirements from historic inpatient settings may differ from modern outpatient settings and therefore may not be appropriate to guide current therapeutic feeding protocols. We calculated the weight gain and average estimated total daily energy requirement of children successfully treated for uncomplicated severe acute malnutrition as outpatients in Niger (n = 790). Mean energy provided by six therapeutic feeding protocols was calculated and compared with average estimated energy requirements in the study population. Overall weight gain was 5.5 g·kg(−1)·day(−1) among recovered children. Average energy requirements ranged from 92 to 110 kcal·kg(−1)·day(−1) depending on the estimation approach. Two current therapeutic feeding protocols were found to provide an excess of energy after the first week of treatment in our study population, whereas four research protocols tended to provide less energy than the estimated requirement after the first week of treatment. Alternative feeding protocols have the potential to simplify and lead to important savings for programmes but should be evaluated to show adequacy to meet the energy needs of children under treatment, as well as feasibility and cost efficiency. Our findings rely on theoretical calculations based on several assumptions and should be confirmed in field studies. John Wiley and Sons Inc. 2020-03-07 /pmc/articles/PMC7507348/ /pubmed/32144946 http://dx.doi.org/10.1111/mcn.12989 Text en © 2020 The Authors. Maternal & Child Nutrition published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Isanaka, Sheila
Andersen, Christopher T.
Hanson, Kerstin E.
Berthé, Fatou
Grais, Rebecca F.
Briend, André
Energy needs in the treatment of uncomplicated severe acute malnutrition: Secondary analysis to optimize delivery of ready‐to‐use therapeutic foods
title Energy needs in the treatment of uncomplicated severe acute malnutrition: Secondary analysis to optimize delivery of ready‐to‐use therapeutic foods
title_full Energy needs in the treatment of uncomplicated severe acute malnutrition: Secondary analysis to optimize delivery of ready‐to‐use therapeutic foods
title_fullStr Energy needs in the treatment of uncomplicated severe acute malnutrition: Secondary analysis to optimize delivery of ready‐to‐use therapeutic foods
title_full_unstemmed Energy needs in the treatment of uncomplicated severe acute malnutrition: Secondary analysis to optimize delivery of ready‐to‐use therapeutic foods
title_short Energy needs in the treatment of uncomplicated severe acute malnutrition: Secondary analysis to optimize delivery of ready‐to‐use therapeutic foods
title_sort energy needs in the treatment of uncomplicated severe acute malnutrition: secondary analysis to optimize delivery of ready‐to‐use therapeutic foods
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507348/
https://www.ncbi.nlm.nih.gov/pubmed/32144946
http://dx.doi.org/10.1111/mcn.12989
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