Autoimmunity gene IRGM suppresses cGAS‐STING and RIG‐I‐MAVS signaling to control interferon response

Activation of the type 1 interferon response is extensively connected to the pathogenesis of autoimmune diseases. Loss of function of Immunity Related GTPase M (IRGM) has also been associated to several autoimmune diseases, but its mechanism of action is unknown. Here, we found that IRGM is a master...

Descripción completa

Detalles Bibliográficos
Autores principales: Jena, Kautilya Kumar, Mehto, Subhash, Nath, Parej, Chauhan, Nishant Ranjan, Sahu, Rinku, Dhar, Kollori, Das, Saroj Kumar, Kolapalli, Srinivasa Prasad, Murmu, Krushna C, Jain, Ashish, Krishna, Sivaram, Sahoo, Bhabani Sankar, Chattopadhyay, Soma, Rusten, Tor Erik, Prasad, Punit, Chauhan, Swati, Chauhan, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507369/
https://www.ncbi.nlm.nih.gov/pubmed/32715615
http://dx.doi.org/10.15252/embr.202050051

Ejemplares similares

Ejemplares similares