Wedelolactone facilitates Ser/Thr phosphorylation of NLRP3 dependent on PKA signalling to block inflammasome activation and pyroptosis

OBJECTIVES: Wedelolactone exhibits regulatory effects on some inflammatory diseases. However, the anti‐inflammatory mechanism of wedelolactone has not been entirely unravelled. Therefore, the present study focuses on investigating the mechanism of wedelolactone on NLRP3 inflammasome in macrophages a...

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Detalles Bibliográficos
Autores principales: Pan, Hao, Lin, Yuqing, Dou, Jianping, Fu, Zhen, Yao, Yanqing, Ye, Shanyu, Zhang, Saixia, Wang, Neng, Liu, Aijun, Li, Xican, Zhang, Fengxue, Chen, Dongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507381/
https://www.ncbi.nlm.nih.gov/pubmed/32656909
http://dx.doi.org/10.1111/cpr.12868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507381/
https://www.ncbi.nlm.nih.gov/pubmed/32656909
http://dx.doi.org/10.1111/cpr.12868

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