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A Biomimetic Approach toward Enhancing Angiogenesis: Recombinantly Expressed Domain V of Human Perlecan Is a Bioactive Molecule That Promotes Angiogenesis and Vascularization of Implanted Biomaterials

Angiogenic therapy involving delivery of pro‐angiogenic growth factors to stimulate new blood vessel formation in ischemic disease is promising but has seen limited clinical success due to issues associated with the need to deliver supra‐physiological growth factor concentrations. Bio‐inspired growt...

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Detalles Bibliográficos
Autores principales: Lin, Xiaoting, Tang, Fengying, Jiang, Shouyuan, Khamis, Heba, Bongers, Andre, Whitelock, John M., Lord, Megan S., Rnjak‐Kovacina, Jelena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507460/
https://www.ncbi.nlm.nih.gov/pubmed/32995122
http://dx.doi.org/10.1002/advs.202000900

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