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A Biomimetic Approach toward Enhancing Angiogenesis: Recombinantly Expressed Domain V of Human Perlecan Is a Bioactive Molecule That Promotes Angiogenesis and Vascularization of Implanted Biomaterials
Angiogenic therapy involving delivery of pro‐angiogenic growth factors to stimulate new blood vessel formation in ischemic disease is promising but has seen limited clinical success due to issues associated with the need to deliver supra‐physiological growth factor concentrations. Bio‐inspired growt...
Autores principales: | Lin, Xiaoting, Tang, Fengying, Jiang, Shouyuan, Khamis, Heba, Bongers, Andre, Whitelock, John M., Lord, Megan S., Rnjak‐Kovacina, Jelena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507460/ https://www.ncbi.nlm.nih.gov/pubmed/32995122 http://dx.doi.org/10.1002/advs.202000900 |
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