A Lactose‐Derived CRISPR/Cas9 Delivery System for Efficient Genome Editing In Vivo to Treat Orthotopic Hepatocellular Carcinoma

Gene editing is a crucial and effective strategy to treat genetic diseases. Safe and effective delivery vectors are specially required for efficient gene editing in vivo of CRISPR/Cas9 system. Interestingly, lactose, a natural saccharide, can specifically bind to asialoglycoprotein receptors, highly...

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Detalles Bibliográficos
Autores principales: Qi, Yu, Liu, Yanli, Yu, Bingran, Hu, Yang, Zhang, Nasha, Zheng, Yan, Yang, Ming, Xu, Fu‐Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507475/
https://www.ncbi.nlm.nih.gov/pubmed/32995132
http://dx.doi.org/10.1002/advs.202001424

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